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IMPORTANT DATES
Abstract Submission Deadline
August 20, 2021
Early Registration until
August 27, 2021
Late Registration after
August 27, 2021
AWARDS
NOTE
A special issue will be published in connection with Phytochemistry Reviews (SCI-exp., impact factor: 5.374) for the selected presentations in Natural Products session
REGISTRATION

Daewoo Han

University Of Cincinnati

BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors.
Follow this format for each person.  DO NOT EXCEED FIVE PAGES.

NAME: Han, Daewoo

eRA COMMONS USER NAME (credential, e.g., agency login): handaewoo

POSITION TITLE: Senior Research Associate, PhD

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION DEGREE

(if applicable)

 

Completion Date

MM/YYYY

 

FIELD OF STUDY

 

Hoseo University, South Korea B. S. 02/1996 Telecommunication
Hoseo University, South Korea M. S. 08/1998 Telecommunication / Optics
University of Cincinnati, Cincinnati, OH Ph. D. 12/2010 Electrical Engineering
University of Cincinnati, Cincinnati, OH Postdoc 09/2013 Electrical Engineering
  1. Personal Statement 

I have been conducting research in the field of nanotechnology and point-of-care diagnostics since I started research activities in the University of Cincinnati as a PhD student in 2004. Over the last 16 years, I have worked in several areas applying multi-functional nanofiber membranes, which led to multiple breakthrough findings and outcomes. My novel approaches as well as research conclusions have been internationally cited and utilized to develop variants in various applications and to understand the fundamental science. Currently, I am working as a Senior Research Associate and Adjust Instructor at the University of Cincinnati, serving as a highly motivated multidisciplinary research engineer with outstanding laboratory skills and methodical approaches, leading to high impact outcomes and awards upon synergistic collaborations with various institutes such as the Johns Hopkins Hospital, University of Health Sciences and Pharmacy in St. Louis, P&G, UC medical and other UC departments.

 

My application-oriented research is mainly focused on two categories: development of electrospun nanofiber applications and paper-based point-of-care diagnostic devices. Many articles in high impact journals ~ 42 articles (mostly ranked in top 10% in the field), 22 oral presentations, 30 poster presentations, and 2 US patents have been made upon my successful research outcomes. As a post-doctoral fellow, a competitive-based research fund award was granted to me in 2011 and the proposed project was implemented successfully by publishing a high impact article in ACS Applied Materials and Interfaces, cited 133 times since 2013 based on Google Scholar.

 

Current research activities are mainly focused on development of multi-axially electrospun nanofiber applications such as (1) “on-demand” programmable drug delivery system for wound dressing and localized cocktail chemotherapy, (2) non-hormonal contraceptive nanofibers, (3) mobile electrospinning system for dura repair, and (4) membrane-based microfluidic devices for point-of-care diagnostics.

 

  1. Positions and Honors 

Positions

2018-present     Adjunct Instructor, Dept. of Electrical Engineering, University of Cincinnati, OH.

2014-present     Senior Research Associate, Dept. of Electrical Engineering, University of Cincinnati, OH.

2013-14              Research Associate, Department of Electrical Engineering, University of Cincinnati, OH.

Honors, awards, service

2007-2009                  Nanomedicine Center Scholarship, University of Cincinnati

2008                            3rd Place Poster Award, Midwest Tissue Engineering Consortium.

2009                            Best in Show Poster Award, Graduate Poster Forum.

2009                            First prize awarded in honor of Professor Darrell Reneker’s 80th Birthday, Material Research Society Fall Meeting.

2011                            Postdoctoral Fellow Research Fund (competitive-base), University Research Council.

2014                            Invited speaker, 9th International Meeting on Electrowetting and Related Micro/Electrofluidic Science and Technology, Cincinnati, OH USA

2014                           Editorial Board of Universal Journal of Electrical and Electronic Engineering.

2015                           Editorial Board of the Nanomedicine & Nanoscience Research.

2017                           Invited speaker on “Electrospinning: an overview and applications” at the MSE (Material Science and Engineering) Seminar Series, University of Cincinnati

2017                           Nomination for MRS Best Poster Award.

2020                           Invited speaker, IEEE RAPID conference, Miramar Beach, FL.

 

 

  1. Contributions to Science

I have been recognized in the electrospinning research area as one of leading researcher, especially in coaxial electrospinning research. Using coaxial electrospinning, I have first demonstrated the superhydrophobic and oleophobic membranes by fabricating Teflon coated nanofibers in one step, which was the first to demonstrate coaxial fibers with non-electrospinnable polymer solution in sheath. This breakthrough journal article has been cited ~ 315 times as of October 2019. Similar strategy has been utilized with non-electrospinnable enzyme in sheath to protect soldiers from anti-warfare agent in the battlefield. Another breakthrough in the field has been accomplished by demonstrating the dual drug release from tri-layered coaxial nanofiber membranes. Combining the burst release and the controlled release into a single delivery system leads a synergistic effect and opens the door to many biomedical applications including cancer therapy, wound dressing and tissue engineering. In 2017, I have demonstrated the “on-demand” drug release from nanofiber membranes triggered by external stimuli such as pH values, which potentially beneficial for cancer researches, receiving many citations in the field. Currently, we are collaborating with the world-renowned medical team in the Johns Hopkins University to develop the novel local cancer therapy for deadly brain cancers and our promising results was published in Nature Scientific Report in 2019. I also published the comprehensive review article about coaxial electrospinning, which was selected as Very Important Paper and Cover feature. My research outcomes have been cited ~ 1060 times as of May 2020. Related publications are listed below.

 

  • Han and A. J. Steckl, “Coaxial Electrospinning Formation of Complex Polymer Fibers and their Applications”, ChemPlusChem, 84, pp. 1453-1497, 2019.
  • Han, R. Serra, N. Gorelick, U. Fatima, C. G. Eberhart, H. Brem, B. Tyler and A. J. Steckl, "Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor”, Sci. Rep., 9, 17936, 2019.
  • Han and A. J. Steckl, “Selective pH Responsive Coaxial Nanofiber Membranes for Chem/Bio/Med Applications: Targeted Delivery of Functional Molecules”, ACS Appl. Mater. Interfaces, 9, pp. 42653-42660, 2017.
  • Han, M. Sasaki, A. Sasaki, and A. J. Steckl, “In-vitro evaluation of MPA-Loaded electrospun coaxial fiber membranes for local treatment of glioblastoma tumor cells”, J. Drug Deliv. Sci. Technol. 40, pp. 40-45, 2017.

 

 

 

 

 

  1. Additional Information: Research Support and/or Scholastic Performance

 

Ongoing Research Support

 

National Institutes of Health                                                          Pauletti (PI)                                                   7/1/2020 ~ 6/30/2022

SMART Polymer Fibers for Tampon-like Nonsteroidal Contraceptive Devices

Develop the ‘steroid-free’ bio-responsive contraception device using nanofiber membranes.

Role: Main researcher

 

National Institutes of Health                                                          Pauletti (PI)                                                   8/1/2019 ~ 7/31/2024

SMART Polymer Fibers for Tampon-like Nonsteroidal Contraceptive Devices

Develop the ‘steroid-free’ bio-responsive contraception device using nanofiber membranes.

Role: Main researcher

 

Procter & Gamble Company                                                          Steckl (PI)                                                                 9/1/2019 ~ 8/31/2021

Organic Electrochemical Transistors as Bacterial Biosensors

Development of organic electrochemical transistors to detect bacterial infection in products.

Role: Senior researcher

 

Procter & Gamble Company                                                          Steckl (PI)                                                                 7/1/2021 ~ 6/30/2022

Development of Aptamer Sensors for Endotoxin Detection

Development of sandwiched aptamer-based lateral flow assay for detecting endotoxins in human saliva.

Role: Main researcher

 

 

Completed Research Support

 

University of Cincinnati                                                                 Steckl (PI)                                                                 10/1/2017 ~ 9/30/2019

Bioresponsive Nanofibers – SMART Multi-purpose Prevention Technology for Women

Interdisciplinary research between engineering, pharmacy and hospital to develop smart bioresponsive contraception using nanofibers, preventing unintended pregnancies and sexually transmitted infections.

Role: Main researcher

 

Cambridge Display Technology, Ltd.                   Steckl (PI)                                                                 4/1/2016 ~ 6/30/2017

Electrospinning of Multi-Layer Fibers for Controlled Release of Active Materials

Develop the new food packaging material to prevent from ripening of high value products.

Role: Senior researcher

 

Procter & Gamble Company                                                          Steckl (PI)                                                                 1/1/2020 ~ 12/31/2020

Fluid Volume Sensor Using Fiber Membrane Pressure Transducer

Developing highly sensitive piezoelectric pressure sensor to monitor the fluid volume in various containers.

Role: Senior researcher

 


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